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Sunday, December 27, 2020

Sleeping pills

 Sleeping pills 

What Are Sleeping Pills? 

A sleeping pill may be effective at ending your sleep problems short-term. But it's important to make sure you understand everything you need to know about sleeping pills and is side effect. 

Most sleeping pills are classified as "sedative hypnotics." That's a specific class of drugs used to induce and/or maintain sleep. Sedative hypnotics include benzodiazepines, barbiturates, and various hypnotics. 


Benzodiazepines such as Xanax, Valium, Ativan, and Librium are anti-anxiety medications. They also increase drowsiness and help people sleep. Halcion is an older benzodiazepine sedative-hypnotic medicine that has largely been replaced by newer medicines? While these drugs may be useful short-term, all benzodiazepines are potentially addictive and can cause problems with memory and attention. They are usually not recommended for long-term treatment of sleeping problems. 

Barbiturates, another drug in this sedative-hypnotic class, depress the central nervous system and can cause sedation. Short- or long-acting barbiturates are prescribed as sedatives or sleeping pills. But more commonly, these hypnotic drugs are limited to use as anaesthesia. They can be fatal in overdose. 

Newer medications help reduce the time it takes to fall asleep. Some of these sleep-inducing drugs, which bind to the same receptors in the brain as do benzodiazepines, include Lunesta, Sonata, and Ambien. They are somewhat less likely than benzodiazepines to be habit-forming, but over time can still sometimes cause physical dependence. They can work quickly to increase drowsiness and sleep. Another sleep aid, called Rozerem, acts differently from other sleep medicines by affecting a brain hormone called melatonin, and is not habit-forming. Belsomra is another unique sleep aid that affects a brain chemical called orexin, and is not addictive or habit-forming. Another sleep medicine that is not habit-forming, Silenor, is a low-dose form of the tricyclic antidepressant doxepin. 

What Are the Side Effects of Sleeping Pills? 

Your doctor may be able to alert you to the possibility of side effects if you have asthma or other health conditions. Sleeping pills can interfere with normal breathing and can be dangerous in people who have certain chronic lung problems such as asthma , emphysema, or forms of chronic obstructive pulmonary disease (COPD). 

Common side effects of prescription sleeping pills such as Lunesta, Sonata, Ambien, Rozerem and Halcion may include: 

  • Burning or tingling in the hands, arms, feet, or legs 

  • Changes in appetite 

  • Constipation 

  • Diarrhoea 

  • Difficulty keeping balance 

  • Heartburn 

  • Impairment the next day 

  • Mental slowing or problems with attention or memory 

  • Stomach pain or tenderness 

  • Uncontrollable shaking of a part of the body 

It's important to be aware of possible sleeping pill side effects so you can stop the drug and call your doctor immediately to avoid a more serious health problem. 

 

Q.1. What is mean by "sedative hypnotics."? 

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Q.2. write the name of two drugs used as a sleeping pill. 

a.------------------------------------- 

b.------------------------------------- 

Q.3. Common side effects of sleeping pills such as (any four) 

----------------------------- 

----------------------------- 

------------------------------- 

-------------------------------- 

Q.4. Sleeping pills can interfere with normal breathing and can be dangerous in people who have certain chronic lung problems such ----------- and ----------- 

Q.5. What message you will get after reading this para? Write down about it. 

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ANSWERS: - 

 

  1. Full Credit: - specific class of drugs used to induce and/or maintain sleep                                                                                           Nil Credit: - No answer or any wrong answer 

  1. Full Credit: - Any two 

           Half Credit: - For any one  

Nil credit: - No answer or any wrong answer 

  1. Full Credit: - any four  

Half Credit: - For any two  

Nil Credit. : - No answer or any wrong answer 

  1. Full Credit: - asthma , emphysema  

Half Credit: - For any one  

Nil Credit. : - No Answer or any other Answer 

  1. Full credit- health related awareness  

 

Immunisation

Immunisation

The  purpose of immunisation is to prevent people from acquiring  infections  and to protect  them  against  short  and  long  term  complications  of  those  infections . Vaccines   work by stimulating  bodies defence mechanism against  infections . These defence mechanism are collectively  referred  to as bodies immune system .  The great  advantage of immunisation over natural infection is that immunisation has a much lower risk  of  adverse  outcomes .

                Immune system consists of trillions of  specialised  blood cells known as WBCs  and their products known as  antibodies . These cells are  located  throughout  the body not only in blood stream ,but also in lymph glands ,spleen ,skin ,lungs and  intestine . The skin and lining of  lungs are the first  line  of defence against  infections .These tissues and  WBCs  located  at  these  sites  form innate immune system .WBCs  of  innate immune system detect  the presence of  infection using sensors on their surfaces  that  recognise  parts of  pathogen  or toxins released  by them .These fragments  from pathogen or toxins  are collectively called  antigens .

              Lymphocytes  are  categorised  into two types -  B cells  and  T cells .  T cells respond to infections  by releasing  chemicals called  cytokine  and  B- cells  prepare  complex  proteins called  Antibodies which attach  in lock  and  key fashion either  to pathogen or to toxin released by  them .

 

      Vaccine contain  weakened  pathogens  or  antigens which generally do not have power  to  cause  disease .

    Most   of  cells  involved  in  immune responses  live for  only  a few days  but small  number of lymphocytes survive for months or years  after  infection has been cleared  and  retain a memory  of invading pathogens .

          Bodies immune system begins developing before birth .Maternal  antibodies cross the placenta into babies circulation  before birth  and  are present in mother’s milk  .Measles  containing vaccine (MMR) is not given  until 12 months of age ,when maternal antibodies against   measles  which can interfere  with vaccine  responses have  essentially  disappeared .The following chart  shows  the schedule  of vaccination in children –



Question  1 : Immunisation

Developing  immunity against a disease  through vaccine is comparatively safer  than the immunity developed due to natural  infection . Give your arguments in favour or  against of  the given statement .

...............................................................................................................................

..............................................................................................................................................................................................................................................................

Question 2 :  Immunisation                                                                                               Which  of  the following  vaccines  is given at the time of birth  to  an infant  -

 i) BCG ,Hepatitis – B  

ii) MMR

iiI) Hepatitis – A 

iv) Rotavirus  vaccine

 

Question 3 : Immunisation

Cells  responsible  for immunity  are short  lived but  the  immunity  developed  after  vaccination lasts for a very long  duration . How could it be possible ?

.............................................................................................................................................................................................................................................................................................................................................................................................

Question 4  :Immunisation

 Why  do you  think  a particular vaccine should be administered  at  a  specific age  and  not  randomly  at any  time ?

............................................................................................................................

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Scoring    key 

Question  1 :  Immunisation

i) Vaccine  contains  weakened pathogen or antigen which do not  have  power to cause disease  but  natural infection has active pathogens which can cause  disease  -     Full  Credit

ii) Any  other  answer   -    No credit

Question  2 :  Immunisation

Ans  (i)  BCG  and  Hepatitis B

Question 3:  Immunisation

(i) Small  number  of  lymphocytes  survive for a very  long duration  after  infection has been cleared  and  keeps  the memory  of  invading pathogen .              Full  Credit

(ii) Immune  system works  on memory  of infection -      Partial  Credit

(iii) Any other  answer  -     No Credit

Question  4:  Immunisation

(i)  Maternal  antibodies  present  in infants blood may  interfere  with  vaccine   -  Full  Credit

(ii) Any  other  answer   -           No  Credit         

Saturday, December 26, 2020

IMMUNE SYSTEM

 

IMMUNE SYSTEM

     After Covid-19 we all are familiar with the word-Immune system. The Immune System is a complex network of cells and proteins that defends the body against infections. The immune system detects a wide variety of agents from viruses to parasitic worms, known as pathogens. Immune system has the ability to distinguish pathogens from healthy tissue in our body.

     The main part of the immune system is white blood cells, which produces antibodies. Antibodies are chemically proteins. Antibodies fight with pathogens (microbes) or toxins (poisons) they produce. White blood cells are produced in bone marrow and move throughout the body looking for foreign bodies (microbes). Healthy diet and regular exercise boost up our immune system.



   The immune system keeps a record of every germ (microbe) it has ever defeated, so it can recognize and destroy the microbe quickly if it enters the body .“Vaccines” work on this principle.

    Vaccines contain a microorganism in a weekend live or killed state, or proteins or toxins from the organism, which stimulate the immune system to produce antibodies. The processes of administration of a vaccine are known as “Vaccination” (Immunization).

Q 2.1    Antibodies are chemically made up of:

    (a)   Sugar  

    (b)   Protein

    (c)   Vitamin

    (d)   Fat

Q2.2    Which part of blood forms antibodies?

    (a)    Red blood cells

    (b)   White blood cells

   (c)     Platelets

   (d)    Plasma

Q 2.3   In which part of our body are White blood cells formed?

Q 2.4   The Vaccine triggers -------------- to form antibodies.(fill in the blanks)

Q 2.5    Give two examples of common vaccines?

Answer and scoring--

1.1

Option   (d) Nitrogen

Full credit: 2

Any other option no credit

1.2

Option   (d) Cyanobacteria 

Full credit: 2

Any other option no credit

1.3

Legumes

Full credit: 2

Half credit :1(for one example such as

                         Pea, Gram)

1.4

Azotobacter, Anabaena, Nostoc (any one)

Full credit: 2

For any other suitable examples full credit

1.5

Full credit: 2     (for two reasons)

Half credit :1    (for one reason)

2.1

Option   (b) Protein 

Full credit: 2

Any other option no credit

2.2

Option   (b) White blood cells

Full credit: 2

Any other option no credit

2.3

Bone marrow

Full credit: 2

2.4

White blood cells

Full credit: 2

2.5

Full credit:2   (For two correct examples)

Half credit :1   (For one correct example)



BIOFERTILIZERS

 

BIOFERTILIZERS

Bio fertilizers are artificially multiplied cultures of certain microorganisms that can improve soil fertility and crop productivity without polluting our environment. Some common microorganisms used as bio fertilizers are Rhizobium, Azotobacter, Azospirillum, Blue green algae (Cyanobacteria) etc. These microorganisms fix atmospheric nitrogen, converting insoluble phosphates into soluble and decomposable farm wastes, which results in the release of plant nutrients by their biological activities.

       Rhizobium forms nodules in the roots of legume plants and fixes atmospheric nitrogen symbiotically. Azotobacter is a free living nitrogen fixing bacteria present in soil which enhances the crop yield of cereals by fixing nitrogen non symbiotically. Anabaena & Nostoc belonging to Cyanobacteria are free living nitrogen fixing microbes mainly used in rice fields to enhance crop yield.



     These microbes are produced in large scale and used in crop fields as a bio- fertilizer to supplement the chemical fertilizers to maintain sustainability of the soil and environment. It is cheaper than chemical fertilizer.


Q 1.1 Bio fertilizers are used to maintain which element in soil:

 (a) Calcium    

 (b)  Magnesium

 (c)   Iron

 (d)   Nitrogen

 Ans- d

Q 1.2   Blue green algae are known as:

(a)     Bacteria

(b)    Algae

(c)     Lichen

(d)    Cyanobacteria

 Ans- d

Q 1.3 In which group of plants does Rhizobium form nodules?

Ans-legume plants

Q 1.4   Give one example of microbe which fixes nitrogen in cereal crops.

Ans- Azotobacter ,Anabaena & Nostoc

Q 1.5   How bio fertilizers are better than chemical fertilizers? Give two reasons.

Ans-   These microbes are produced in large scale and used in crop fields as a bio- fertilizer to supplement the chemical fertilizers to maintain sustainability of the soil and environment. It is cheaper than chemical fertilizer


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